2934. Systemic Conditions Releted To Kidneys,Liver &Gall Bladder 2) Chronic Kidney Disease

Chronic Kidney Disease

Chronic kidney disease (CKD) means your kidneys are damaged and can't filter blood the way they should. The main risk factors for developing kidney disease are diabetes, high blood pressure, heart disease, and a family history of kidney failure.

#Symptoms

Symptoms can include:

weight loss and poor appetite.

swollen ankles, feet or hands – as a result of water retention (oedema)

shortness of breath.

tiredness.

blood in your pee (urine)

an increased need to pee – particularly at night.

difficulty sleeping (insomnia)

itchy skin.

Early stages of CKD

Kidney disease does not tend to cause symptoms when it's at an early stage.

This is because the body is usually able to cope with a significant reduction in kidney function.

Kidney disease is often only diagnosed at this stage if a routine test for another condition, such as a blood or urine test, detects a possible problem.

If it's found at an early stage, medicine and regular tests to monitor it may help stop it becoming more advanced.

Later stages of CKD

A number of symptoms can develop if kidney disease is not found early or it gets worse despite treatment.

Symptoms can include:

weight loss and poor appetite

swollen ankles, feet or hands – as a result of water retention (oedema)

shortness of breath

tiredness

blood in your pee (urine)

an increased need to pee – particularly at night

difficulty sleeping (insomnia)

itchy skin

muscle cramps

feeling sick

headaches

The recommended supplements for Chronic Kidney Disease are: Resveratrol,

1. Resveratrol

Resveratrol, a natural compound found in various plants, has gained significant attention in recent years for its potential benefits in managing chronic kidney disease (CKD). CKD is a progressive condition characterized by the gradual loss of kidney function, leading to various complications. Resveratrol has been extensively studied for its antioxidant, anti-inflammatory, and anti-fibrotic properties, which are crucial in the context of CKD. Studies have shown that resveratrol can help reduce oxidative stress, inflammation, and fibrosis in the kidneys, thereby slowing down the progression of CKD. Additionally, resveratrol has been found to have protective effects on renal cells, promoting their survival and preventing cell death. This compound also exhibits vasodilatory properties, which can improve blood flow to the kidneys and enhance renal function. Moreover, resveratrol has been shown to modulate various signaling pathways involved in CKD pathogenesis, such as the renin-angiotensin-aldosterone system and the nuclear factor-kappa B pathway. These actions contribute to the overall renoprotective effects of resveratrol.

Suggested Use: Take one (1) veggie capsule twice a day as a dietary supplement. For best results, take 20-30 min before a meal or as directed by your healthcare professional.

2. CoQ10

CoQ10, a naturally occurring antioxidant, plays a crucial role in energy production within cells and has been found to be deficient in individuals with CKD. Studies have shown that CoQ10 supplementation can improve kidney function, reduce inflammation, and decrease oxidative stress in CKD patients. Additionally, CoQ10 has been found to have a positive impact on blood pressure control, a common concern in individuals with CKD. Furthermore, research suggests that CoQ10 may help protect against kidney damage caused by certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and certain antibiotics.

Suggested Use: Take one (1) capsule twice a day as a dietary supplement. For best results, take 20-30 min before a meal or as directed by your healthcare professional.

3. Vitamin D3

Vitamin D3 plays a crucial role in maintaining bone health and calcium homeostasis, and its deficiency is commonly observed in CKD patients due to impaired kidney function. However, emerging research suggests that vitamin D3 supplementation may offer more than just skeletal benefits in this population. Studies have shown that vitamin D3 supplementation in CKD patients can help improve cardiovascular health by reducing blood pressure, decreasing arterial stiffness, and mitigating inflammation. Additionally, vitamin D3 has been linked to enhanced immune function, reduced proteinuria, and a possible protective effect against kidney fibrosis. These findings have sparked interest in the potential use of vitamin D3 as an adjunct therapy for CKD patients.